First and most obviously, SA does not have toposophic levels like OA, at least not up to Cognitech 5, and as a result much of the technology that OA would call transapientech can be developed by what OA classifies as modosophonts.
Secondly and relatedly, where OA has achailects and lower transapients ruling most of the setting, those sorts of giant computers/ascended beings do not appear to exist in SA, outside of the Aia and Transcendentals. This is probably just a difference in social histories, looking SA it seems reasonable to suppose it didn't happen like in OA because of bad luck. My guess the Transcendentals Desired Future looks similar to OA in this respect, lots of newly ascended beings looking out for a revitalized (trans)humanity.
If they did exist, all technology that is implied to be in the future would've been developed a long time ago.
As far as Capabilities go:
Biotech: OA does not have immortality without treatments, and looking at the page of Superior genemods, they seem to be a solid Biotech 3. However, on the civilization as opposed to personal level they do have quite impressive biotech, just maybe not to the degree as SA.
On another hand, they do have asomnia, which while not explicitly to not exist in SA, if it did would've probably been mentioned either in the Biotech section or in the Needs box (one of the needs requires sleep). Although it could just be uncommon ATM like in OA.
Chronotech: This does not seem to be a thing that exists in OA.
Cognitech: Modosophonts in SA seem to get much better performance from Cognitech before hitting the toposophic barrier, due to it seemingly not existing. On the other hand, no giant superitelligent computers like in OA. The Stored sorta count, but they're still not as smart as in OA. So overall seems mixed.
Metatech: Overall Metatech looks much more powerful in SA. Psychohistory for example is impractical in OA even for the ascended beings, while it's a standard and highly effective thing for modosophonts in SA.
Nanotech: I'm not really positive, but they seem about on par, maybe.
Stringtech: While OA does have achailect level stuff like basement universes, overall its level of Stringtech seems much lower. They don't have most 4-5 tech, they do have transmutation but it's much less efficient. SA also has remote wormholes while OA only has local.
Another setting difference is uplifts. Uplifts are ubiqitous and important in OA, but if they exist in SA they're not as common or important, as they would've been mentioned in the Mechanicans' Humanity CV otherwise. But as with asomnia above, I prefer to to headcanon SA as being the same as OA in terms of uplifting ubiquity and significance, as I really like the idea of uplifting.
I'm sure there's a bunch of other stuff, but OA is a pretty big worldbuilding project so I'm only passingly familar with it.